DAILY CURRENT AFFAIRS IAS | UPSC Prelims and Mains Exam – 26th February 2024
Archives (PRELIMS & MAINS Focus) ANTIMICROBIAL RESISTANCE Syllabus Prelims & Mains – Science Context: Kerala recently initiated Operation AMRITH (Antimicrobial Resistance Intervention for Total Health). This programme enforces rule mandating a doctor’s prescription for acquiring any class of antibiotics. Background:- Kerala has pioneered many public health initiatives in the country with significant investment in the sector About ANTIMICROBIAL RESISTANCE Antimicrobials – including antibiotics, antivirals, antifungals and antiparasitics – are medicines used to prevent and treat infections in humans, animals and plants. Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death. As a result of drug resistance, antibiotics and other antimicrobial medicines become ineffective and infections become increasingly difficult or impossible to treat. AMR occurs naturally over time, usually through genetic changes. Antimicrobial resistant organisms are found in people, animals, food, plants and the environment (in water, soil and air). They can spread from person to person or between people and animals, including from food of animal origin. The main drivers of antimicrobial resistance include the misuse and overuse of antimicrobials; lack of access to clean water, sanitation and hygiene (WASH) for both humans and animals; poor infection and disease prevention and control in health-care facilities and farms; poor access to quality, affordable medicines, vaccines and diagnostics; lack of awareness and knowledge; and lack of enforcement of legislation. Source: The Hindu Schedule H and H1 Syllabus Prelims – Current Event Context: Kerala recently initiated Operation AMRITH (Antimicrobial Resistance Intervention for Total Health). This programme enforces rule mandating a doctor’s prescription for acquiring any class of antibiotics. Background:- Schedule H1 is particularly relevant to prevent misuse of drugs, one of the causes of antimicrobial resistance. Schedule H and H1 The Drugs and cosmetic Act, 1940 was passed in British India to regulate the manufacture, distribution, and sale of drugs in the country. After Indian independence, the Act underwent various amendments from time to time. The act classifies drugs into different schedules. What are Schedule H Drugs? This schedule contains a list of drugs that can be sold only against the prescription of a registered medical practitioner. Another provision needs to be followed is that, only the required amount of medications mentioned in the prescription can be dispensed. These drugs can be supplied only to the licensed parties. The drug label must exhibit the text “Rx” and Schedule H drug warning: To be sold by retails on the prescription of a Registered Medical Practioner only. Why was Schedule H1 Introduced A newer category created in 2013 as a sub-classification of Schedule H. These drugs are also prescription-only but face additional regulations compared to Schedule H. The schedule H1 drugs was mainly created to restrict the selling of antibiotics through over the counter (OTC) sales, after it was noted that any number of these drugs could be bought from pharmacies across India without any limitations. Irrational prescribing of antibiotics and other drugs by doctors and chemists lacking a registered pharmacist has contributed to the increasing antibiotics resistance and tolerance of psychotropics. The Supply of a drug specified in Schedule H1 shall be recorded in a separate register at the time of the supply giving the name and address of the prescriber, the name of the patient, the name of the drug and the quantity supplied and such record shall be maintained for three years and be open for inspection. Both Schedule H and H1 drugs are prescription-only, but Schedule H1 has stricter regulations due to the specific types of drugs included and the potential for misuse or public health concerns. The additional labeling and record-keeping requirements for Schedule H1 aim to enhance control and ensure responsible usage of these medications. Source: The Hindu Trisomy Syllabus Prelims – Science Context: Researchers have reported chromosomal disorders discovered from prehistoric skeletal remains, dating up to approximately 5,500 years old — including six cases of Down syndrome and one case of Edwards syndrome. Background: There have only been a few documented cases of Down syndrome in ancient individuals, largely owing to difficulties in identifying genetic disorders without modern techniques for analysing ancient DNA samples About Trisomy: Chromosomes are the threadlike structures in cells that hold genes. Genes carry the instructions needed to make every part of a baby’s body. When an egg and sperm join and form an embryo, their chromosomes combine. Each baby gets 23 chromosomes from the mother’s egg and 23 chromosomes from the father’s sperm — 46 in total.i.e.humans have 23 pairs of chromosomes. Trisomy is a chromosomal abnormality where an individual has three copies of a particular chromosome instead of the usual two copies. This can occur in any chromosome, but some are more common than others. The most common type of trisomy is trisomy 21, also known as Down syndrome. Other common types include trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). These conditions can cause a variety of physical and intellectual disabilities, although the severity of symptoms can vary widely from person to person. Source: The Hindu INDUS WATER TREATY Syllabus Prelims – Current Event Context: India completely stops Ravi River water flow to Pakistan. Background: The completion of the Shahpur Kandi barrage diverts water from the Ravi River to benefit Jammu and Kashmir. This project, under the Indus Waters Treaty, aids irrigation and hydropower generation, contributing to agricultural and economic growth in the region. About INDUS WATER TREATY The Indus Water Treaty is a water-sharing agreement between India and Pakistan, brokered by the World Bank and signed in 1960. The treaty was signed by then Indian Prime Minister Jawaharlal Nehru and Pakistani President Ayub Khan. The treaty deals with the river Indus and its five tributaries, classified into two categories: Eastern rivers: Ravi, Beas, Sutlej Western rivers: Indus, Chenab, Jhelum India got control over the eastern rivers, while Pakistan got control over the western rivers. The treaty allows India to use the
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